Full price comparison · US & Canada

Depakote (Divalproex Sodium Er) Rx Price Comparison: US vs Canada — Save Up to 90% in the US

Brand availableRx requiredAvailable US & Canadatablet extended release 24 hourHealth Canada DIN 00596434

Cheaper in the US

0%

lower price for Divalproex Sodium Er, based on the lowest comparable per-unit prices we found

US · discount card

$21.20

per fill

Lowest listed pharmacy price

Lowest

US · Cost Plus Drugs

$0.030

per unit

Published price, no card needed

Canada

$0.290

per tablet

Lowest listed pharmacy price

Fetching live USD → CAD rate…

US pharmacy prices — 250mg

PharmacyDiscount-card priceRegular cash priceAverage retail
Food Lion$21.20Lowest$21.20$11.99
Walmart Neighborhood Market$22.16$25.16$11.99
Walmart Pharmacy$22.16$25.16$11.99
Walgreens$22.98$25.98$11.99
Costco$25.25$25.25$11.99
CVS Pharmacy$26.73$29.73$11.99
Kroger Pharmacy$26.77$29.77$11.99
Harris Teeter Pharmacy$26.77$29.77$11.99
Publix$28.56$28.56$11.99

"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.

Canadian pharmacy prices

Initial · 250 mgfrom $21.33
PharmacyPrice / tabletPack sizeShippingTotal
LifeRxPharmacy.com$0.290150$14.95$43.25Lowest
LifeRxPharmacy.com$0.320120$14.95$38.06
medsengage.com$0.32090$14.95$29.09
CanadianPharmacyAdvantage.com$0.330100Free$32.78
medsengage.com$0.36060$14.95$21.33
CanadaPharmacies.com$0.440100Free$43.99
CanadianPrescriptionDrugstore.com$0.47090$14.95$42.00
BuyLowDrugs.com$0.630100$0.00$63.00
Initial · 500 mgfrom $32.06
PharmacyPrice / tabletPack sizeShippingTotal
LifeRxPharmacy.com$0.310150$14.95$46.00Lowest
LifeRxPharmacy.com$0.340120$14.95$40.48
medsengage.com$0.49090$14.95$43.71
CanadianPharmacyAdvantage.com$0.500150Free$74.85
medsengage.com$0.53060$14.95$32.06
CanadaPharmacies.com$0.570150Free$85.99
CanadianPrescriptionDrugstore.com$0.670100$14.95$67.00
Initial · 1000 mgfrom $55.65
PharmacyPrice / tabletPack sizeShippingTotal
OffShoreCheapMeds.com$0.77090$14.95$69.56Lowest
medsengage.com$0.82090$14.95$73.91
OffShoreCheapMeds.com$0.93060$14.95$55.65
medsengage.com$0.99060$14.95$59.13
Generic · 500 mgfrom $42.85
PharmacyPrice / tabletPack sizeShippingTotal
CanadianPrescriptionDrugstore.com$0.420150$14.95$63.00Lowest
CanadianPharmacyAdvantage.com$0.500150Free$74.61
LifeRxPharmacy.com$0.530120$14.95$63.04
LifeRxPharmacy.com$0.55090$14.95$49.68
CanadaPharmacies.com$0.570150Free$85.99
InhalersOnline.com$0.820$0.00$123.20
CanadaPharmacyPro.com$1.01180$14.95$181.00
CanadaPharmacyPro.com$1.0690$14.95$95.82
InhalersOnline.com$2.86$0.00$42.85
Brand · 500 mgfrom $42.85
PharmacyPrice / tabletPack sizeShippingTotal
CanadianPrescriptionDrugstore.com$0.420150$14.95$63.00Lowest
CanadianPharmacyAdvantage.com$0.500150Free$74.61
LifeRxPharmacy.com$0.530120$14.95$63.04
LifeRxPharmacy.com$0.55090$14.95$49.68
CanadaPharmacies.com$0.570150Free$85.99
InhalersOnline.com$0.820$0.00$123.20
CanadaPharmacyPro.com$1.01180$14.95$181.00
CanadaPharmacyPro.com$1.0690$14.95$95.82
InhalersOnline.com$2.86$0.00$42.85

Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.

Interchangeable forms

Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Divalproex Sodium Er.

Other brand names
Depakote
Generic clinical forms
24 HR divalproex sodium 250 MG Extended Release Oral Tablet

Frequently asked questions

How much does Divalproex Sodium Er (Depakote) cost without insurance?

Our most recent US pharmacy data shows a low of roughly $21.20 for Divalproex Sodium Er with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.

Is Divalproex Sodium Er (Depakote) available through Cost Plus Drugs?

Yes — Cost Plus Drugs lists Divalproex Sodium Er at roughly $0.030 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.

What do Canadian pharmacies charge for Divalproex Sodium Er (Depakote)?

We found Canadian pricing for Divalproex Sodium Er starting near $0.290 per tablet in USD terms. That's before any shipping charge, which the table above breaks out separately.

Why is Divalproex Sodium Er (Depakote) priced differently in the US and Canada?

Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.

Is a generic form of Depakote ER available?

Yes. Depakote ER is the brand-name version of divalproex sodium extended-release, manufactured by AbbVie Inc. The generic equivalent is available.

What is Depakote ER used to treat?

Depakote ER is an extended-release anticonvulsant from the fatty acid derivative drug class. It is primarily prescribed to treat various types of seizure disorders, manage manic episodes in bipolar disorder, and help prevent migraine headaches. The medication works by helping to restore the balance of certain neurotransmitters in the brain. It is crucial to discuss your full medical history with your doctor before starting this medication, as it is contraindicated in people with certain liver diseases, urea cycle disorders, or specific genetic conditions like Alpers' disease. Special precautions are necessary for individuals with a history of depression, mental illness, or mitochondrial disorders. Due to a high risk of serious birth defects and potential long-term effects on a child's development, the use of Depakote ER during pregnancy requires careful management and should never be started or stopped without direct medical supervision.

What side effects are associated with Depakote ER?

Common side effects of Depakote ER can include nausea, vomiting, stomach discomfort, diarrhea, headache, dizziness, weakness, tremors, coordination problems, blurred vision, and changes in appetite or weight. A serious and potentially fatal risk is liver failure, which is of particular concern for children under two years old and individuals with certain genetic mitochondrial disorders. This is not a complete list of possible adverse effects. Always consult your healthcare provider for advice on managing any side effects you experience.