Esbriet (Pirfenidone) Rx Price Comparison: US vs Canada — Save Up to 23% in Canada

Our most recent US pharmacy data shows a low of roughly $219.82 for Pirfenidone with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.

Yes — Cost Plus Drugs lists Pirfenidone at roughly $0.491 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.

We found Canadian pricing for Pirfenidone starting near $0.380 per tablet in USD terms. That's before any shipping charge, which the table above breaks out separately.

Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the Canadian price coming in lower — but that isn't true for every drug, so it's worth checking each medication individually rather than assuming.

Your copay for Esbriet with insurance will vary depending on the specifics of your plan. It is advisable to ask your pharmacist to compare your insurance copay against the price you could obtain using a discount card or coupon, as the latter may sometimes offer a lower out-of-pocket cost.

Most Medicare Part D and Medicare Advantage plans include Esbriet on their formularies, but patient copays can still be substantial. For those without coverage or facing high copays, exploring alternative savings options, such as manufacturer coupons or pharmacy discount programs, can help reduce the cost.

Esbriet is the brand name for the medication pirfenidone. As of now, a generic version of pirfenidone is not available in the United States.