Full price comparison · US & Canada
Esbriet Prices — US Pharmacy Cost vs Canada — Save Up to 47% in the US
Cheaper in the US
0%
lower price for Pirfenidone, based on the lowest comparable per-unit prices we found
US · discount card
$219.82
per fill
Lowest listed pharmacy price
US · Cost Plus Drugs
$0.491
per unit
Published price, no card needed
Canada
$0.930
per tablet
Lowest listed pharmacy price
US pharmacy prices — 801mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Walgreens | $219.82Lowest | $222.82 | $880.59 |
 Food Lion | $904.40 | $904.40 | $880.59 |
 Costco | $1,421.20 | $1,421.20 | $880.59 |
 Publix | $5,601.01 | $5,604.01 | $3,333.09 |
 Kroger Pharmacy | $8,747.99 | $8,750.99 | $880.59 |
 Harris Teeter Pharmacy | $8,747.99 | $8,750.99 | $880.59 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Canadian pharmacy prices
Initial · 267 mgfrom $94.50
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
 CanadianPrescriptionDrugstore.com | $2.17 | 270 | $14.95 | $585.00Lowest |
 SPFPharmacy.com | $2.33 | 270 | $9.95 | $629.99 |
 InhalersOnline.com | $2.41 | 270 | $0.00 | $649.99 |
| CanadianPrescriptionDrugstore.com | $2.48 | 90 | $14.95 | $223.00 |
 CanadianPharmacyAdvantage.com | $2.55 | 90 | Free | $229.43 |
 CanadaPharmacyPro.com | $2.59 | 90 | $14.95 | $233.00 |
 CanadaPharmacies.com | $2.67 | 90 | Free | $239.99 |
| CanadaPharmacyPro.com | $2.74 | 60 | $14.95 | $164.47 |
| SPFPharmacy.com | $4.50 | 21 | $9.95 | $94.50 |
| InhalersOnline.com | $5.00 | 21 | $0.00 | $104.99 |
Initial · 400 mgfrom $51.80
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| CanadianPrescriptionDrugstore.com | $0.930 | 540 | $14.95 | $500.00Lowest |
 LifeRxPharmacy.com | $0.930 | 810 | $14.95 | $751.28 |
| $0.980 | 810 | $14.95 | $791.61 | |
| LifeRxPharmacy.com | $0.990 | 540 | $14.95 | $534.24 |
| $1.04 | 540 | $14.95 | $562.92 | |
 OffShoreCheapMeds.com | $1.20 | 810 | $14.95 | $968.75 |
| OffShoreCheapMeds.com | $1.28 | 540 | $14.95 | $688.89 |
 GoldStarMeds.com | $1.73 | 30 | $0.00 | $51.80 |
 1800RxOnline.com | $1.92 | 30 | $0.00 | $57.55 |
| CanadaPharmacyPro.com | $2.92 | 90 | $14.95 | $263.08 |
| CanadaPharmacyPro.com | $3.10 | 45 | $14.95 | $139.28 |
Initial · 600 mgfrom $251.31
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| CanadianPrescriptionDrugstore.com | $1.31 | 540 | $14.95 | $708.00Lowest |
| CanadianPrescriptionDrugstore.com | $1.33 | 270 | $14.95 | $360.00 |
| $1.74 | 810 | $14.95 | $1,407.17 | |
| OffShoreCheapMeds.com | $1.75 | 810 | $14.95 | $1,418.48 |
| LifeRxPharmacy.com | $1.76 | 540 | $14.95 | $950.40 |
| $1.85 | 540 | $14.95 | $1,000.65 | |
| LifeRxPharmacy.com | $1.94 | 270 | $14.95 | $522.72 |
| OffShoreCheapMeds.com | $2.80 | 360 | $14.95 | $1,008.69 |
| CanadaPharmacyPro.com | $3.96 | 90 | $14.95 | $356.02 |
| CanadaPharmacyPro.com | $4.19 | 60 | $14.95 | $251.31 |
Initial · 801 mgfrom $80.60
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| CanadianPrescriptionDrugstore.com | $1.38 | 810 | $14.95 | $1,121.00Lowest |
| LifeRxPharmacy.com | $1.39 | 810 | $14.95 | $1,125.90 |
| CanadianPrescriptionDrugstore.com | $1.41 | 540 | $14.95 | $760.00 |
| InhalersOnline.com | $1.42 | 600 | $0.00 | $850.02 |
| LifeRxPharmacy.com | $1.48 | 540 | $14.95 | $800.64 |
| $1.52 | 810 | $14.95 | $1,234.93 | |
| $1.63 | 540 | $14.95 | $878.17 | |
| GoldStarMeds.com | $1.65 | 90 | $0.00 | $148.83 |
| 1800RxOnline.com | $1.84 | 90 | $0.00 | $165.37 |
| InhalersOnline.com | $2.00 | 100 | $0.00 | $199.99 |
| OffShoreCheapMeds.com | $2.43 | 810 | $14.95 | $1,964.66 |
| OffShoreCheapMeds.com | $2.59 | 540 | $14.95 | $1,397.09 |
| GoldStarMeds.com | $2.69 | 30 | $0.00 | $80.60 |
| 1800RxOnline.com | $2.99 | 30 | $0.00 | $89.55 |
| CanadianPharmacyAdvantage.com | $6.31 | 270 | Free | $1,703.13 |
| CanadaPharmacies.com | $6.34 | 270 | Free | $1,712.99 |
| CanadianPharmacyAdvantage.com | $6.45 | 90 | Free | $580.65 |
| CanadaPharmacies.com | $6.56 | 90 | Free | $589.99 |
| SPFPharmacy.com | $7.00 | 90 | $9.95 | $629.99 |
| InhalersOnline.com | $7.22 | 90 | $0.00 | $649.99 |
| CanadaPharmacyPro.com | $10.36 | 270 | $14.95 | $2,798.30 |
| CanadaPharmacyPro.com | $11.75 | 90 | $14.95 | $1,057.13 |
Generic · 801 mgfrom $1,555.18
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| CanadianPrescriptionDrugstore.com | $15.33 | 270 | $14.95 | $4,138.00Lowest |
| OffShoreCheapMeds.com | $15.55 | 270 | $14.95 | $4,198.98 |
| OffShoreCheapMeds.com | $17.28 | 90 | $14.95 | $1,555.18 |
| GoldStarMeds.com | $19.20 | 90 | $0.00 | $1,728.19 |
| 1800RxOnline.com | $21.34 | 90 | $0.00 | $1,920.21 |
| GoldStarMeds.com | $49.41 | 90 | $0.00 | $4,446.78 |
| 1800RxOnline.com | $54.90 | 90 | $0.00 | $4,940.87 |
Brand · 801 mgfrom $1,555.18
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| CanadianPrescriptionDrugstore.com | $15.33 | 270 | $14.95 | $4,138.00Lowest |
| OffShoreCheapMeds.com | $15.55 | 270 | $14.95 | $4,198.98 |
| OffShoreCheapMeds.com | $17.28 | 90 | $14.95 | $1,555.18 |
| GoldStarMeds.com | $19.20 | 90 | $0.00 | $1,728.19 |
| 1800RxOnline.com | $21.34 | 90 | $0.00 | $1,920.21 |
| GoldStarMeds.com | $49.41 | 90 | $0.00 | $4,446.78 |
| 1800RxOnline.com | $54.90 | 90 | $0.00 | $4,940.87 |
Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Pirfenidone.
Frequently asked questions
Is Pirfenidone (Esbriet) expensive if I don't have insurance?
At the US pharmacies in our data, the lowest listed discount-card price for Pirfenidone is around $219.82. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
Can I buy Pirfenidone (Esbriet) at a Cost Plus Drugs price?
Yes — Cost Plus Drugs lists Pirfenidone at roughly $0.491 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.
How much does Pirfenidone (Esbriet) cost in Canada?
Canadian pharmacy listings in our data show Pirfenidone priced from about $0.930 per tablet (converted to USD), before shipping. Pack size and pharmacy both affect the final total — see the Canada pricing table for specifics.
Why does Pirfenidone (Esbriet) cost more in one country than the other?
Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.
How much does Esbriet cost with insurance?
Your copay for Esbriet with insurance will vary depending on the specifics of your plan. It is advisable to ask your pharmacist to compare your insurance copay against the price you could obtain using a discount card or coupon, as the latter may sometimes offer a lower out-of-pocket cost.
Does Medicare cover Esbriet and how much does it cost?
Most Medicare Part D and Medicare Advantage plans include Esbriet on their formularies, but patient copays can still be substantial. For those without coverage or facing high copays, exploring alternative savings options, such as manufacturer coupons or pharmacy discount programs, can help reduce the cost.
Is there a generic of Esbriet?
Esbriet is the brand name for the medication pirfenidone. As of now, a generic version of pirfenidone is not available in the United States.