Full price comparison · US & Canada
How Much Does Lupron Depot Cost?
Price comparison
See both prices
We don't have a directly comparable per-unit price for Lupron Depot yet — the full breakdown is below.
US · discount card
$1,851.56
per fill
Lowest listed pharmacy price
Canada
$154.06
per tablet
Lowest listed pharmacy price
US pharmacy prices — 3.75mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
| $1,851.56Lowest | $1,854.56 | $2,289.40 | |
| $1,851.56Lowest | $1,854.56 | $2,289.40 | |
| $1,944.09 | $1,947.09 | $2,285.99 | |
| $1,959.68 | $1,959.68 | $2,274.59 | |
| $1,999.07 | $2,002.07 | $2,269.40 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Canadian pharmacy prices
Initial · Defaultfrom $259.99
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $233.33 | — | $0.00 | $699.99Lowest | |
| $259.99 | — | $0.00 | $259.99 |
Generic · 3.75 mgfrom $163.13
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $154.06 | — | Free | $462.18Lowest | |
| $157.66 | — | Free | $472.99 | |
| $163.13 | — | Free | $163.13 | |
| $173.99 | — | Free | $173.99 | |
| $621.42 | — | $0.00 | $1,864.26 | |
| $629.73 | — | $0.00 | $629.73 |
Generic · 7.5 mgfrom $474.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $474.00 | — | $14.95 | $474.00Lowest | |
| $492.98 | — | $0.00 | $492.98 | |
| $546.21 | — | $0.00 | $1,638.63 | |
| $547.75 | — | $0.00 | $547.75 | |
| $563.13 | — | $0.00 | $563.13 | |
| $587.46 | — | $0.00 | $1,762.38 | |
| $609.83 | — | $0.00 | $609.83 |
Generic · 22.5 mgfrom $1,191.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $1,191.00 | — | $14.95 | $1,191.00Lowest | |
| $1,478.78 | — | $0.00 | $4,436.34 | |
| $1,500.99 | — | $0.00 | $1,500.99 |
Generic · 30 mgfrom $1,660.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $1,660.00 | — | $14.95 | $1,660.00Lowest | |
| $1,929.76 | — | $0.00 | $5,789.28 | |
| $1,936.78 | — | $0.00 | $1,936.78 | |
| $2,032.55 | — | $0.00 | $6,097.65 | |
| $2,055.49 | — | $0.00 | $2,055.49 |
Brand · 3.75 mgfrom $163.13
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $154.06 | — | Free | $462.18Lowest | |
| $157.66 | — | Free | $472.99 | |
| $163.13 | — | Free | $163.13 | |
| $173.99 | — | Free | $173.99 | |
| $621.42 | — | $0.00 | $1,864.26 | |
| $629.73 | — | $0.00 | $629.73 |
Brand · 7.5 mgfrom $474.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $474.00 | — | $14.95 | $474.00Lowest | |
| $492.98 | — | $0.00 | $492.98 | |
| $546.21 | — | $0.00 | $1,638.63 | |
| $547.75 | — | $0.00 | $547.75 | |
| $563.13 | — | $0.00 | $563.13 | |
| $587.46 | — | $0.00 | $1,762.38 | |
| $609.83 | — | $0.00 | $609.83 |
Brand · 22.5 mgfrom $1,191.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $1,191.00 | — | $14.95 | $1,191.00Lowest | |
| $1,478.78 | — | $0.00 | $4,436.34 | |
| $1,500.99 | — | $0.00 | $1,500.99 |
Brand · 30 mgfrom $1,660.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $1,660.00 | — | $14.95 | $1,660.00Lowest | |
| $1,929.76 | — | $0.00 | $5,789.28 | |
| $1,936.78 | — | $0.00 | $1,936.78 | |
| $2,032.55 | — | $0.00 | $6,097.65 | |
| $2,055.49 | — | $0.00 | $2,055.49 |
Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Lupron Depot.
Frequently asked questions
How much does Lupron Depot (Lupron Depot) cost without insurance?
Our most recent US pharmacy data shows a low of roughly $1,851.56 for Lupron Depot with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.
What do Canadian pharmacies charge for Lupron Depot (Lupron Depot)?
We found Canadian pricing for Lupron Depot starting near $154.06 per tablet in USD terms. That's before any shipping charge, which the table above breaks out separately.
Why is Lupron Depot (Lupron Depot) priced differently in the US and Canada?
Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. Check the comparison table above for the specific numbers on Lupron Depot.
Does Lupron Depot have a generic equivalent?
Generic and brand-name pricing for Lupron Depot is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
How much will I pay for Lupron Depot if I have health insurance, Medicare, or Medicaid?
The out-of-pocket cost for Lupron Depot with insurance depends entirely on the specifics of your plan's formulary and benefit design. Coverage, copays, and coinsurance can vary significantly. You should contact your insurance provider directly for details on your medication coverage and estimated cost. If your plan does not cover Lupron Depot, or if your copay is high, you may be able to use a pharmacy savings program to obtain a lower price. Similarly, patients with Medicare or Medicaid can check if these savings programs offer a price lower than their government benefit plan's cost-sharing requirements. Comparing the price available through a savings program with your insurance price can help identify the most affordable option.
Is a generic version of Lupron Depot available?
No. Lupron Depot is a brand-name medication, and a generic (bioequivalent) form of leuprolide acetate in this depot formulation is not currently available in the United States.