Leuprolide Acetate (Leuprolide Acetate) Rx Price Comparison: US vs Canada — Save Up to 90% in the US

At the US pharmacies in our data, the lowest listed discount-card price for Leuprolide Acetate is around $229.86. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.

Yes — Cost Plus Drugs lists Leuprolide Acetate at roughly $51.32 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.

Canadian pharmacy listings in our data show Leuprolide Acetate priced from about $496.83 per tablet (converted to USD), before shipping. Pack size and pharmacy both affect the final total — see the Canada pricing table for specifics.

Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.

Leuprolide is generally not covered under Medicare Part D prescription drug plans. Instead, coverage is typically provided under Medicare Part B as a medically administered service. This means your cost would be subject to the Part B deductible and coinsurance. The final price you pay can be influenced by whether the administering facility accepts discount programs, which may offer a lower cash price for the medication.

Leuprolide is the generic name for the active ingredient itself. It is the component found in brand-name drugs like Eligard, which is used to treat advanced prostate cancer.

Leuprolide is a generic hormone therapy medication. It is the active ingredient in brand-name drugs such as Eligard, primarily prescribed for men with advanced prostate cancer. As a palliative treatment, it helps slow cancer progression but does not offer a cure. It functions by significantly reducing the production of male hormones like testosterone. Since these hormones fuel the growth of prostate cancer cells, blocking their production inhibits cancer cell division. The medication is also used off-label for certain conditions in women, such as endometriosis or uterine fibroids, as it can prevent the release of estrogen, a hormone linked to these conditions. Leuprolide is administered as a subcutaneous injection by a healthcare professional, with formulations designed to release the medication continuously over two, four, or six months.