Megestrol Acetate (Megestrol Acetate) Rx Price Comparison: US vs Canada — Save Up to 91% in the US

Our most recent US pharmacy data shows a low of roughly $43.02 for Megestrol Acetate with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.

Yes — Cost Plus Drugs lists Megestrol Acetate at roughly $0.122 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.

We found Canadian pricing for Megestrol Acetate starting near $1.38 per tablet in USD terms. That's before any shipping charge, which the table above breaks out separately.

Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.

Generic megestrol is typically covered under Medicare Part D and Medicare Advantage prescription drug plans. However, the brand-name versions Megace and Megace ES may not be covered. Costs for Medicare beneficiaries will depend on their specific plan's phase of coverage (deductible, initial coverage, etc.). For those without Medicare drug coverage, using a pharmacy savings program or discount card can provide a way to access the medication at a reduced cash price.

Megestrol is the generic name for the medication. It is also marketed under the brand names Megace and Megace ES, which are manufactured by Bristol-Myers Squibb. The generic version is produced by several pharmaceutical companies, including Teva and Par Pharmaceuticals.

Megestrol is a synthetic progestin, a man-made version of the female hormone progesterone. It is primarily prescribed to stimulate appetite and promote weight gain in patients experiencing severe, illness-related weight loss and malnutrition, a condition sometimes called wasting syndrome. Its appetite-stimulating effects are often noticed within a day or two of starting treatment. The weight gain is primarily due to increased body fat. Megestrol is also used as a hormonal therapy for certain cancers, including breast cancer and endometrial cancer (cancer of the uterus lining), where it works by reducing the body's production of hormones that fuel cancer growth. It is administered as an oral suspension.