US pharmacy pricing

Opsynvi Prices at US Pharmacies

Brand availableRx requiredUS pricing onlytablet

Lowest price found · US pharmacies

$12,353.39/fill

for Opsynvi, across the pharmacies in our data

US pharmacy prices — 10-40mg

PharmacyDiscount-card priceRegular cash priceAverage retail
Kroger Pharmacy$12,353.39Lowest$12,356.39$388.65
Harris Teeter Pharmacy$12,353.39Lowest$12,356.39$388.65
Walgreens$12,994.39$12,997.39$388.65
Publix$13,075.54$13,078.54$388.65
Walmart Neighborhood Market$13,312.77$13,315.77$388.65
Walmart Pharmacy$13,312.77$13,315.77$388.65
Costco$13,392.17$13,395.17$388.65
Food Lion$13,592.07$13,592.07$388.65

"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.

Interchangeable forms

Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Opsynvi.

Generic clinical forms
macitentan 10 MG / tadalafil 20 MG Oral Tablet

Frequently asked questions

What's the cash price for Opsynvi (Opsynvi) in the US?

Our most recent US pharmacy data shows a low of roughly $12,353.39 for Opsynvi with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.

Does Opsynvi have a generic equivalent?

Generic and brand-name pricing for Opsynvi is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.

How much does Opsynvi cost with insurance?

Insurance coverage for Opsynvi varies significantly between plans, and some may not cover it at all. Your out-of-pocket cost with insurance depends on your specific plan's formulary, deductibles, and copay or coinsurance structure. It is essential to contact your insurance provider directly to confirm your coverage details. If your insurance does not cover Opsynvi, or if your copay is high, you may be able to use a pharmacy savings card to lower your cost at participating pharmacies. These cards can also be an option for individuals with Medicare or Medicaid if those programs do not cover your prescription. To find the most affordable price, compare the cost using your insurance against the price available with a savings card at your pharmacy.

Is generic Opsynvi available?

No. Opsynvi is a brand-name medication manufactured by Actelion Pharmaceuticals. A generic equivalent is not currently on the market.