Full price comparison · US & Canada
Entresto (Sacubitril-Valsartan) Rx Price Comparison: US vs Canada — Save Up to 84% in the US
Cheaper in the US
0%
lower price for Sacubitril-Valsartan, based on the lowest comparable per-unit prices we found
US · discount card
$30.70
per fill
Lowest listed pharmacy price
US · Cost Plus Drugs
$0.105
per unit
Published price, no card needed
Canada
$0.660
per tablet
Lowest listed pharmacy price
US pharmacy prices — 24-26mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 CVS Pharmacy | $30.70Lowest | $33.70 | $11.99 |
 Publix | $47.83 | $47.83 | $11.99 |
 Food Lion | $54.20 | $54.20 | $11.99 |
 Walgreens | $62.08 | $65.08 | $11.99 |
 Kroger Pharmacy | $413.71 | $416.71 | $11.99 |
 Harris Teeter Pharmacy | $413.71 | $416.71 | $11.99 |
 Walmart Neighborhood Market | $444.33 | $447.33 | $11.99 |
 Walmart Pharmacy | $444.33 | $447.33 | $11.99 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Canadian pharmacy prices
Initial · 49/51 (100) mgfrom $44.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
 CanadianPrescriptionDrugstore.com | $0.660 | 180 | $14.95 | $119.00Lowest |
 GoldStarMeds.com | $0.680 | 180 | $0.00 | $121.95 |
| GoldStarMeds.com | $0.680 | 180 | $0.00 | $122.85 |
 CanadianPharmacyAdvantage.com | $0.690 | 210 | Free | $145.73 |
| RxOutreach.org | $0.730 | 60 | $0.00 | $44.00 |
 1800RxOnline.com | $0.750 | 180 | $0.00 | $135.50 |
 CanadaPharmacies.com | $0.750 | 210 | Free | $156.99 |
| 1800RxOnline.com | $0.760 | 180 | $0.00 | $136.50 |
 CanadaPharmacyPro.com | $0.760 | 168 | $14.95 | $128.38 |
| CanadianPharmacyAdvantage.com | $0.790 | 70 | Free | $55.40 |
 LifeRxPharmacy.com | $0.790 | 168 | $14.95 | $132.66 |
| $0.790 | 168 | $14.95 | $132.66 | |
 InhalersOnline.com | $0.810 | 180 | $0.00 | $145.02 |
 OffShoreCheapMeds.com | $0.810 | 168 | $14.95 | $135.51 |
| CanadaPharmacyPro.com | $0.850 | 56 | $14.95 | $47.55 |
| LifeRxPharmacy.com | $0.880 | 56 | $14.95 | $49.13 |
| $0.880 | 56 | $14.95 | $49.13 | |
| OffShoreCheapMeds.com | $0.900 | 56 | $14.95 | $50.19 |
| CanadaPharmacies.com | $0.940 | 70 | Free | $65.99 |
| GoldStarMeds.com | $0.940 | 60 | $0.00 | $56.44 |
| GoldStarMeds.com | $1.00 | 60 | $0.00 | $59.85 |
| 1800RxOnline.com | $1.05 | 60 | $0.00 | $62.71 |
| 1800RxOnline.com | $1.11 | 60 | $0.00 | $66.50 |
| InhalersOnline.com | $1.67 | 30 | $0.00 | $49.99 |
 SPFPharmacy.com | $4.03 | 180 | $9.95 | $724.50 |
| SPFPharmacy.com | $4.20 | 60 | $9.95 | $252.00 |
| InhalersOnline.com | $4.49 | 180 | $0.00 | $807.99 |
| InhalersOnline.com | $5.08 | 60 | $0.00 | $304.99 |
Initial · 97/103 (200) mgfrom $44.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| RxOutreach.org | $0.730 | 60 | $0.00 | $44.00Lowest |
| CanadianPrescriptionDrugstore.com | $0.780 | 180 | $14.95 | $141.00 |
| GoldStarMeds.com | $0.790 | 180 | $0.00 | $141.75 |
| 1800RxOnline.com | $0.880 | 180 | $0.00 | $157.50 |
| CanadianPharmacyAdvantage.com | $1.08 | 210 | Free | $227.01 |
| CanadaPharmacies.com | $1.13 | 210 | Free | $237.99 |
| GoldStarMeds.com | $1.18 | 60 | $0.00 | $70.65 |
| LifeRxPharmacy.com | $1.28 | 168 | $14.95 | $215.03 |
| 1800RxOnline.com | $1.31 | 60 | $0.00 | $78.50 |
| CanadaPharmacyPro.com | $1.32 | 168 | $14.95 | $221.55 |
| CanadianPharmacyAdvantage.com | $1.32 | 35 | Free | $46.37 |
| $1.40 | 168 | $14.95 | $235.88 | |
| InhalersOnline.com | $1.41 | 180 | $0.00 | $253.02 |
| LifeRxPharmacy.com | $1.41 | 112 | $14.95 | $157.69 |
| OffShoreCheapMeds.com | $1.41 | 168 | $14.95 | $236.52 |
| CanadaPharmacyPro.com | $1.45 | 112 | $14.95 | $162.47 |
| $1.54 | 112 | $14.95 | $172.98 | |
| OffShoreCheapMeds.com | $1.56 | 56 | $14.95 | $87.60 |
| CanadaPharmacies.com | $1.63 | 35 | Free | $56.99 |
| InhalersOnline.com | $2.33 | 30 | $0.00 | $69.99 |
| SPFPharmacy.com | $4.20 | 180 | $9.95 | $756.00 |
| SPFPharmacy.com | $4.38 | 60 | $9.95 | $262.50 |
| InhalersOnline.com | $4.49 | 180 | $0.00 | $807.99 |
| InhalersOnline.com | $5.08 | 60 | $0.00 | $304.99 |
Generic · 49/51 (100) mgfrom $78.52
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| CanadianPrescriptionDrugstore.com | $1.25 | 168 | $14.95 | $210.00Lowest |
 BuyLowDrugs.com | $1.26 | 196 | $0.00 | $246.00 |
| CanadianPharmacyAdvantage.com | $1.29 | 168 | Free | $217.13 |
| CanadaPharmacyPro.com | $1.32 | 168 | $14.95 | $222.22 |
| LifeRxPharmacy.com | $1.33 | 168 | $14.95 | $223.91 |
| CanadaPharmacies.com | $1.36 | 168 | Free | $227.99 |
| GoldStarMeds.com | $1.39 | 168 | $0.00 | $233.21 |
| CanadaPharmacyPro.com | $1.40 | 84 | $14.95 | $117.65 |
| CanadianPharmacyAdvantage.com | $1.40 | 56 | Free | $78.52 |
| LifeRxPharmacy.com | $1.41 | 84 | $14.95 | $118.54 |
| GoldStarMeds.com | $1.43 | 168 | $0.00 | $240.98 |
| $1.43 | 168 | $14.95 | $239.52 | |
| OffShoreCheapMeds.com | $1.43 | 168 | $14.95 | $240.90 |
| $1.51 | 84 | $14.95 | $126.81 | |
| OffShoreCheapMeds.com | $1.52 | 84 | $14.95 | $127.53 |
| 1800RxOnline.com | $1.54 | 168 | $0.00 | $259.12 |
| 1800RxOnline.com | $1.59 | 168 | $0.00 | $267.76 |
| CanadaPharmacies.com | $1.59 | 56 | Free | $88.99 |
| BuyLowDrugs.com | $2.23 | 168 | $0.00 | $375.00 |
| BuyLowDrugs.com | $2.23 | 168 | $0.00 | $375.00 |
| GoldStarMeds.com | $2.54 | 56 | $0.00 | $142.48 |
| 1800RxOnline.com | $2.83 | 56 | $0.00 | $158.31 |
| GoldStarMeds.com | $3.54 | 168 | $0.00 | $594.68 |
| 1800RxOnline.com | $3.93 | 168 | $0.00 | $660.76 |
| InhalersOnline.com | $4.03 | 168 | $0.00 | $676.32 |
 GreatNorthPharmacy.com | $4.41 | 60 | $14.99 | $264.50 |
| InhalersOnline.com | $4.57 | 168 | $0.00 | $767.34 |
| SPFPharmacy.com | $4.61 | 180 | $9.95 | $828.99 |
| SPFPharmacy.com | $4.63 | 60 | $9.95 | $277.73 |
| InhalersOnline.com | $4.88 | 28 | $0.00 | $136.57 |
| InhalersOnline.com | $5.07 | 56 | $0.00 | $284.01 |
Generic · 97/103 (200) mgfrom $112.54
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| CanadianPrescriptionDrugstore.com | $1.42 | 168 | $14.95 | $239.00Lowest |
| LifeRxPharmacy.com | $1.43 | 168 | $14.95 | $240.01 |
| $1.43 | 168 | $14.95 | $241.03 | |
| OffShoreCheapMeds.com | $1.47 | 168 | $14.95 | $247.61 |
| LifeRxPharmacy.com | $1.51 | 84 | $14.95 | $127.06 |
| $1.52 | 84 | $14.95 | $127.60 | |
| GoldStarMeds.com | $1.62 | 168 | $0.00 | $271.44 |
| OffShoreCheapMeds.com | $1.62 | 112 | $14.95 | $181.58 |
| 1800RxOnline.com | $1.80 | 168 | $0.00 | $301.60 |
| CanadaPharmacyPro.com | $2.17 | 168 | $14.95 | $364.10 |
| CanadaPharmacyPro.com | $2.29 | 84 | $14.95 | $192.76 |
| CanadianPharmacyAdvantage.com | $2.43 | 168 | Free | $407.67 |
| CanadaPharmacies.com | $2.57 | 168 | Free | $431.99 |
| CanadianPharmacyAdvantage.com | $2.66 | 56 | Free | $148.78 |
| CanadaPharmacies.com | $2.95 | 56 | Free | $164.99 |
| GoldStarMeds.com | $3.54 | 168 | $0.00 | $594.68 |
| InhalersOnline.com | $3.66 | 168 | $0.00 | $615.24 |
| 1800RxOnline.com | $3.93 | 168 | $0.00 | $660.76 |
| InhalersOnline.com | $4.02 | 28 | $0.00 | $112.54 |
| GoldStarMeds.com | $4.29 | 168 | $0.00 | $720.58 |
| GoldStarMeds.com | $4.43 | 112 | $0.00 | $495.73 |
| GreatNorthPharmacy.com | $4.58 | 60 | $14.99 | $275.00 |
| SPFPharmacy.com | $4.66 | 180 | $9.95 | $838.89 |
| InhalersOnline.com | $4.71 | 168 | $0.00 | $791.64 |
| 1800RxOnline.com | $4.77 | 168 | $0.00 | $800.64 |
| SPFPharmacy.com | $4.81 | 60 | $9.95 | $288.75 |
| 1800RxOnline.com | $4.92 | 112 | $0.00 | $550.81 |
| InhalersOnline.com | $5.10 | 56 | $0.00 | $285.54 |
Brand · 49/51 (100) mgfrom $78.52
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| CanadianPrescriptionDrugstore.com | $1.25 | 168 | $14.95 | $210.00Lowest |
| BuyLowDrugs.com | $1.26 | 196 | $0.00 | $246.00 |
| CanadianPharmacyAdvantage.com | $1.29 | 168 | Free | $217.13 |
| CanadaPharmacyPro.com | $1.32 | 168 | $14.95 | $222.22 |
| LifeRxPharmacy.com | $1.33 | 168 | $14.95 | $223.91 |
| CanadaPharmacies.com | $1.36 | 168 | Free | $227.99 |
| GoldStarMeds.com | $1.39 | 168 | $0.00 | $233.21 |
| CanadaPharmacyPro.com | $1.40 | 84 | $14.95 | $117.65 |
| CanadianPharmacyAdvantage.com | $1.40 | 56 | Free | $78.52 |
| LifeRxPharmacy.com | $1.41 | 84 | $14.95 | $118.54 |
| GoldStarMeds.com | $1.43 | 168 | $0.00 | $240.98 |
| $1.43 | 168 | $14.95 | $239.52 | |
| OffShoreCheapMeds.com | $1.43 | 168 | $14.95 | $240.90 |
| $1.51 | 84 | $14.95 | $126.81 | |
| OffShoreCheapMeds.com | $1.52 | 84 | $14.95 | $127.53 |
| 1800RxOnline.com | $1.54 | 168 | $0.00 | $259.12 |
| 1800RxOnline.com | $1.59 | 168 | $0.00 | $267.76 |
| CanadaPharmacies.com | $1.59 | 56 | Free | $88.99 |
| BuyLowDrugs.com | $2.23 | 168 | $0.00 | $375.00 |
| BuyLowDrugs.com | $2.23 | 168 | $0.00 | $375.00 |
| GoldStarMeds.com | $2.54 | 56 | $0.00 | $142.48 |
| 1800RxOnline.com | $2.83 | 56 | $0.00 | $158.31 |
| GoldStarMeds.com | $3.54 | 168 | $0.00 | $594.68 |
| 1800RxOnline.com | $3.93 | 168 | $0.00 | $660.76 |
| InhalersOnline.com | $4.03 | 168 | $0.00 | $676.32 |
| GreatNorthPharmacy.com | $4.41 | 60 | $14.99 | $264.50 |
| InhalersOnline.com | $4.57 | 168 | $0.00 | $767.34 |
| SPFPharmacy.com | $4.61 | 180 | $9.95 | $828.99 |
| SPFPharmacy.com | $4.63 | 60 | $9.95 | $277.73 |
| InhalersOnline.com | $4.88 | 28 | $0.00 | $136.57 |
| InhalersOnline.com | $5.07 | 56 | $0.00 | $284.01 |
Brand · 97/103 (200) mgfrom $112.54
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| CanadianPrescriptionDrugstore.com | $1.42 | 168 | $14.95 | $239.00Lowest |
| LifeRxPharmacy.com | $1.43 | 168 | $14.95 | $240.01 |
| $1.43 | 168 | $14.95 | $241.03 | |
| OffShoreCheapMeds.com | $1.47 | 168 | $14.95 | $247.61 |
| LifeRxPharmacy.com | $1.51 | 84 | $14.95 | $127.06 |
| $1.52 | 84 | $14.95 | $127.60 | |
| GoldStarMeds.com | $1.62 | 168 | $0.00 | $271.44 |
| OffShoreCheapMeds.com | $1.62 | 112 | $14.95 | $181.58 |
| 1800RxOnline.com | $1.80 | 168 | $0.00 | $301.60 |
| CanadaPharmacyPro.com | $2.17 | 168 | $14.95 | $364.10 |
| CanadaPharmacyPro.com | $2.29 | 84 | $14.95 | $192.76 |
| CanadianPharmacyAdvantage.com | $2.43 | 168 | Free | $407.67 |
| CanadaPharmacies.com | $2.57 | 168 | Free | $431.99 |
| CanadianPharmacyAdvantage.com | $2.66 | 56 | Free | $148.78 |
| CanadaPharmacies.com | $2.95 | 56 | Free | $164.99 |
| GoldStarMeds.com | $3.54 | 168 | $0.00 | $594.68 |
| InhalersOnline.com | $3.66 | 168 | $0.00 | $615.24 |
| 1800RxOnline.com | $3.93 | 168 | $0.00 | $660.76 |
| InhalersOnline.com | $4.02 | 28 | $0.00 | $112.54 |
| GoldStarMeds.com | $4.29 | 168 | $0.00 | $720.58 |
| GoldStarMeds.com | $4.43 | 112 | $0.00 | $495.73 |
| GreatNorthPharmacy.com | $4.58 | 60 | $14.99 | $275.00 |
| SPFPharmacy.com | $4.66 | 180 | $9.95 | $838.89 |
| InhalersOnline.com | $4.71 | 168 | $0.00 | $791.64 |
| 1800RxOnline.com | $4.77 | 168 | $0.00 | $800.64 |
| SPFPharmacy.com | $4.81 | 60 | $9.95 | $288.75 |
| 1800RxOnline.com | $4.92 | 112 | $0.00 | $550.81 |
| InhalersOnline.com | $5.10 | 56 | $0.00 | $285.54 |
Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Sacubitril-Valsartan.
Frequently asked questions
Is Sacubitril-Valsartan (Entresto) expensive if I don't have insurance?
At the US pharmacies in our data, the lowest listed discount-card price for Sacubitril-Valsartan is around $30.70. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
Can I buy Sacubitril-Valsartan (Entresto) at a Cost Plus Drugs price?
Yes — Cost Plus Drugs lists Sacubitril-Valsartan at roughly $0.105 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.
How much does Sacubitril-Valsartan (Entresto) cost in Canada?
Canadian pharmacy listings in our data show Sacubitril-Valsartan priced from about $0.660 per tablet (converted to USD), before shipping. Pack size and pharmacy both affect the final total — see the Canada pricing table for specifics.
Why does Sacubitril-Valsartan (Entresto) cost more in one country than the other?
Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.
How much can I expect to pay for Entresto with my insurance?
Your out-of-pocket cost for Entresto with insurance depends on your specific plan's formulary, deductible, and copay structure. It is advisable to ask your pharmacist for a price check using your insurance details. In some cases, the final cost after applying a manufacturer coupon or pharmacy discount might be lower than your insurance copay, so comparing both options at the pharmacy is recommended.
Is Entresto covered by Medicare, and what will it cost?
Coverage and cost for Entresto under Medicare vary based on your specific Part D or Medicare Advantage plan, the drug's tier placement on your plan's formulary, and your current coverage phase (e.g., deductible, initial coverage, or gap). You should consult your plan documents for details. The retail price with a pharmacy discount card can sometimes be less than the Medicare copay, so having the pharmacist check both prices can help you identify the lowest available cost.
Is a generic version of Entresto available?
No, a generic equivalent for Entresto is not currently on the market. The medication is manufactured by Novartis Pharmaceuticals Corporation. For brand-name drugs like Entresto, patient assistance programs, manufacturer coupons, and pharmacy discount cards can offer significant savings off the retail price.