Full price comparison · US & Canada
Pifeltro Prices — US Pharmacy Cost vs Canada
Price comparison
See both prices
We don't have a directly comparable per-unit price for Pifeltro yet — the full breakdown is below.
US · discount card
$1,842.20
per fill
Lowest listed pharmacy price
Canada
$22.74
per tablet
Lowest listed pharmacy price
US pharmacy prices — 100mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $1,842.20Lowest | $1,845.20 | $55.20 |
 Harris Teeter Pharmacy | $1,842.20Lowest | $1,845.20 | $55.20 |
 Food Lion | $1,927.23 | $1,927.23 | $55.20 |
 CVS Pharmacy | $1,927.93 | $1,930.93 | $55.20 |
 Walgreens | $1,934.27 | $1,937.27 | $55.20 |
 Publix | $1,946.81 | $1,949.81 | $55.20 |
 Costco | $1,988.97 | $1,991.97 | $55.20 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Canadian pharmacy prices
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $22.74 | 90 | $14.95 | $2,046.87Lowest | |
 SPFPharmacy.com | $22.81 | 90 | $9.95 | $2,052.75 |
 InhalersOnline.com | $23.27 | 90 | $0.00 | $2,094.63 |
| SPFPharmacy.com | $23.59 | 30 | $9.95 | $707.70 |
| $24.01 | 60 | $14.95 | $1,440.39 | |
| InhalersOnline.com | $24.27 | 30 | $0.00 | $727.99 |
 OffShoreCheapMeds.com | $24.37 | 90 | $14.95 | $2,193.07 |
 LifeRxPharmacy.com | $24.69 | 90 | $14.95 | $2,222.31 |
| OffShoreCheapMeds.com | $25.72 | 60 | $14.95 | $1,543.27 |
| LifeRxPharmacy.com | $26.06 | 60 | $14.95 | $1,563.85 |
 CanadianPrescriptionDrugstore.com | $32.28 | 30 | $14.95 | $968.50 |
Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Pifeltro.
Frequently asked questions
How much does Pifeltro (Pifeltro) cost without insurance?
At the US pharmacies in our data, the lowest listed discount-card price for Pifeltro is around $1,842.20. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
How much does Pifeltro (Pifeltro) cost in Canada?
Canadian pharmacy listings in our data show Pifeltro priced from about $22.74 per tablet (converted to USD), before shipping. Pack size and pharmacy both affect the final total — see the Canada pricing table for specifics.
Why does Pifeltro (Pifeltro) cost more in one country than the other?
Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. Check the comparison table above for the specific numbers on Pifeltro.
Is a generic version of Pifeltro available?
Generic and brand-name pricing for Pifeltro is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
Is a generic version of Pifeltro available?
No. Pifeltro is a brand-name drug containing the active ingredient doravirine, and there is currently no FDA-approved generic equivalent.
What is Pifeltro and how is it used?
Pifeltro is a prescription antiretroviral medication used as part of a combination regimen to control HIV-1 infection. It is approved for adults who are beginning HIV treatment or who have already achieved a significant reduction in their viral load with other therapies. The active component, doravirine, works by blocking HIV replication. Suppressing the virus helps prevent the development of serious AIDS-related illnesses, including certain cancers and opportunistic infections. Pifeltro is taken orally as one 100 mg tablet daily, with or without food. The exact dosing may be adjusted based on the other medications in your treatment plan. Always consult your doctor or pharmacist for specific dosing instructions.
What side effects are associated with Pifeltro?
Common side effects include diarrhea, nausea, vomiting, stomach pain, dizziness, difficulty sleeping, and tiredness. Some people may experience unusual dreams or mood changes. A serious but less common side effect involves thyroid function. Allergic reactions are rare but require immediate medical attention if symptoms like rash, swelling, or breathing difficulties occur. This list is not exhaustive, so discuss any concerns about potential side effects with your prescribing doctor.