Full price comparison · US & Canada

Apriso (Mesalamine Er) Rx Price Comparison: US vs Canada — Save Up to 73% in Canada

Brand availableRx requiredAvailable US & Canadacapsule extended release 24 hourHealth Canada DIN 02552426

Cheaper in Canada

0%

lower price for Mesalamine Er, based on the lowest comparable per-unit prices we found

US · discount card

$40.10

per fill

Lowest listed pharmacy price

US · Cost Plus Drugs

$0.656

per unit

Published price, no card needed

Lowest

Canada

$0.040

per tablet

Lowest listed pharmacy price

Fetching live USD → CAD rate…

US pharmacy prices — 0.375gm

PharmacyDiscount-card priceRegular cash priceAverage retail
CVS Pharmacy$40.10Lowest$43.10$20.27
Publix$75.98$75.98$20.27
Walgreens$79.35$82.35$20.27
Costco$84.99$84.99$20.27
Food Lion$89.60$89.60$20.27
Kroger Pharmacy$132.68$135.68$20.27
Harris Teeter Pharmacy$132.68$135.68$20.27
Walmart Neighborhood Market$134.57$137.57$20.27
Walmart Pharmacy$134.57$137.57$20.27

"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.

Canadian pharmacy prices

Initial · Defaultfrom $192.96
PharmacyPrice / tabletPack sizeShippingTotal
GoldStarMeds.com$22.00$0.00$616.01Lowest
1800RxOnline.com$24.45$0.00$684.46
GoldStarMeds.com$27.57$0.00$192.96
1800RxOnline.com$30.63$0.00$214.40
Generic · 1 gfrom $15.58
PharmacyPrice / tabletPack sizeShippingTotal
GoldStarMeds.com$15.58$0.00$15.58Lowest
1800RxOnline.com$17.31$0.00$17.31
Generic · 1.2 gfrom $28.21
PharmacyPrice / tabletPack sizeShippingTotal
CanadianPrescriptionDrugstore.com$0.470360$14.95$170.00Lowest
CanadaPharmacyPro.com$0.470360$14.95$170.46
LifeRxPharmacy.com$0.490360$14.95$174.96
medsengage.com$0.490360$14.95$175.56
LifeRxPharmacy.com$0.520180$14.95$92.95
medsengage.com$0.520180$14.95$93.27
CanadaPharmacyPro.com$0.53090$14.95$47.94
CanadianPharmacyAdvantage.com$0.630360Free$225.90
CanadaPharmacies.com$0.660360Free$236.99
OffShoreCheapMeds.com$0.760360$14.95$275.38
InhalersOnline.com$0.810300$0.00$241.90
RxOutreach.org$0.83060$0.00$50.00
OffShoreCheapMeds.com$0.870180$14.95$156.05
CanadianPharmacyAdvantage.com$0.94030Free$28.21
CanadaPharmacies.com$1.3030Free$38.99
GoldStarMeds.com$1.5530$0.00$46.54
InhalersOnline.com$1.6530$0.00$49.60
1800RxOnline.com$1.7230$0.00$51.71
Generic · 1.6 gfrom $222.60
PharmacyPrice / tabletPack sizeShippingTotal
SPFPharmacy.com$3.51180$9.95$632.10Lowest
SPFPharmacy.com$3.7160$9.95$222.60
Generic · 2 gfrom $16.70
PharmacyPrice / tabletPack sizeShippingTotal
GoldStarMeds.com$16.70$0.00$16.70Lowest
1800RxOnline.com$18.55$0.00$18.55
Generic · 4 g/60 mLfrom $26.48
PharmacyPrice / tabletPack sizeShippingTotal
CanadaPharmacies.com$0.040Free$215.99Lowest
CanadianPharmacyAdvantage.com$0.040Free$205.16
CanadianPharmacyAdvantage.com$0.060Free$26.48
InhalersOnline.com$0.080$0.00$152.10
CanadaPharmacies.com$0.090Free$37.99
InhalersOnline.com$0.750$0.00$44.99
Generic · 400 mgfrom $13.79
PharmacyPrice / tabletPack sizeShippingTotal
CanadaPharmacyPro.com$0.140270$14.95$36.78Lowest
OffShoreCheapMeds.com$0.140270$14.95$36.96
CanadaPharmacyPro.com$0.15090$14.95$13.79
OffShoreCheapMeds.com$0.15090$14.95$13.86
LifeRxPharmacy.com$0.160270$14.95$44.14
medsengage.com$0.170270$14.95$46.20
LifeRxPharmacy.com$0.18090$14.95$16.55
medsengage.com$0.180180$14.95$32.72
CanadianPrescriptionDrugstore.com$0.190270$14.95$52.00
CanadianPharmacyAdvantage.com$0.210360Free$74.08
CanadaPharmacies.com$0.240360Free$84.99
BuyLowDrugs.com$0.2601000$0.00$261.00
InhalersOnline.com$0.290600$0.00$175.02
CanadianPharmacyAdvantage.com$0.50030Free$15.01
InhalersOnline.com$0.530100$0.00$52.99
GoldStarMeds.com$0.660$0.00$330.37
SPFPharmacy.com$0.720600$9.95$431.76
1800RxOnline.com$0.730$0.00$367.08
GoldStarMeds.com$0.76030$0.00$22.82
InhalersOnline.com$0.810600$0.00$487.86
CanadaPharmacies.com$0.83030Free$24.99
1800RxOnline.com$0.85030$0.00$25.36
SPFPharmacy.com$0.900100$9.95$90.30
InhalersOnline.com$0.940100$0.00$93.91
GoldStarMeds.com$0.950$0.00$95.37
1800RxOnline.com$1.06$0.00$105.97
Generic · 500 mgfrom $33.09
PharmacyPrice / tabletPack sizeShippingTotal
CanadianPrescriptionDrugstore.com$0.630200$14.95$126.00Lowest
LifeRxPharmacy.com$0.63090$14.95$56.49
LifeRxPharmacy.com$0.69060$14.95$41.42
OffShoreCheapMeds.com$0.74090$14.95$66.80
OffShoreCheapMeds.com$0.82060$14.95$48.99
medsengage.com$0.83090$14.95$74.53
InhalersOnline.com$0.910300$0.00$272.55
medsengage.com$0.91060$14.95$54.66
CanadaPharmacyPro.com$0.920180$14.95$165.11
CanadaPharmacyPro.com$0.97090$14.95$87.41
GoldStarMeds.com$1.1030$0.00$33.09
InhalersOnline.com$1.12100$0.00$112.11
1800RxOnline.com$1.2330$0.00$36.77
Brand · 1 gfrom $15.58
PharmacyPrice / tabletPack sizeShippingTotal
GoldStarMeds.com$15.58$0.00$15.58Lowest
1800RxOnline.com$17.31$0.00$17.31
Brand · 1.2 gfrom $28.21
PharmacyPrice / tabletPack sizeShippingTotal
CanadianPrescriptionDrugstore.com$0.470360$14.95$170.00Lowest
CanadaPharmacyPro.com$0.470360$14.95$170.46
LifeRxPharmacy.com$0.490360$14.95$174.96
medsengage.com$0.490360$14.95$175.56
LifeRxPharmacy.com$0.520180$14.95$92.95
medsengage.com$0.520180$14.95$93.27
CanadaPharmacyPro.com$0.53090$14.95$47.94
CanadianPharmacyAdvantage.com$0.630360Free$225.90
CanadaPharmacies.com$0.660360Free$236.99
OffShoreCheapMeds.com$0.760360$14.95$275.38
InhalersOnline.com$0.810300$0.00$241.90
RxOutreach.org$0.83060$0.00$50.00
OffShoreCheapMeds.com$0.870180$14.95$156.05
CanadianPharmacyAdvantage.com$0.94030Free$28.21
CanadaPharmacies.com$1.3030Free$38.99
GoldStarMeds.com$1.5530$0.00$46.54
InhalersOnline.com$1.6530$0.00$49.60
1800RxOnline.com$1.7230$0.00$51.71
Brand · 1.6 gfrom $222.60
PharmacyPrice / tabletPack sizeShippingTotal
SPFPharmacy.com$3.51180$9.95$632.10Lowest
SPFPharmacy.com$3.7160$9.95$222.60
Brand · 2 gfrom $16.70
PharmacyPrice / tabletPack sizeShippingTotal
GoldStarMeds.com$16.70$0.00$16.70Lowest
1800RxOnline.com$18.55$0.00$18.55
Brand · 4 g/60 mLfrom $26.48
PharmacyPrice / tabletPack sizeShippingTotal
CanadaPharmacies.com$0.040Free$215.99Lowest
CanadianPharmacyAdvantage.com$0.040Free$205.16
CanadianPharmacyAdvantage.com$0.060Free$26.48
InhalersOnline.com$0.080$0.00$152.10
CanadaPharmacies.com$0.090Free$37.99
InhalersOnline.com$0.750$0.00$44.99
Brand · 400 mgfrom $13.79
PharmacyPrice / tabletPack sizeShippingTotal
CanadaPharmacyPro.com$0.140270$14.95$36.78Lowest
OffShoreCheapMeds.com$0.140270$14.95$36.96
CanadaPharmacyPro.com$0.15090$14.95$13.79
OffShoreCheapMeds.com$0.15090$14.95$13.86
LifeRxPharmacy.com$0.160270$14.95$44.14
medsengage.com$0.170270$14.95$46.20
LifeRxPharmacy.com$0.18090$14.95$16.55
medsengage.com$0.180180$14.95$32.72
CanadianPrescriptionDrugstore.com$0.190270$14.95$52.00
CanadianPharmacyAdvantage.com$0.210360Free$74.08
CanadaPharmacies.com$0.240360Free$84.99
BuyLowDrugs.com$0.2601000$0.00$261.00
InhalersOnline.com$0.290600$0.00$175.02
CanadianPharmacyAdvantage.com$0.50030Free$15.01
InhalersOnline.com$0.530100$0.00$52.99
GoldStarMeds.com$0.660$0.00$330.37
SPFPharmacy.com$0.720600$9.95$431.76
1800RxOnline.com$0.730$0.00$367.08
GoldStarMeds.com$0.76030$0.00$22.82
InhalersOnline.com$0.810600$0.00$487.86
CanadaPharmacies.com$0.83030Free$24.99
1800RxOnline.com$0.85030$0.00$25.36
SPFPharmacy.com$0.900100$9.95$90.30
InhalersOnline.com$0.940100$0.00$93.91
GoldStarMeds.com$0.950$0.00$95.37
1800RxOnline.com$1.06$0.00$105.97
Brand · 500 mgfrom $33.09
PharmacyPrice / tabletPack sizeShippingTotal
CanadianPrescriptionDrugstore.com$0.630200$14.95$126.00Lowest
LifeRxPharmacy.com$0.63090$14.95$56.49
LifeRxPharmacy.com$0.69060$14.95$41.42
OffShoreCheapMeds.com$0.74090$14.95$66.80
OffShoreCheapMeds.com$0.82060$14.95$48.99
medsengage.com$0.83090$14.95$74.53
InhalersOnline.com$0.910300$0.00$272.55
medsengage.com$0.91060$14.95$54.66
CanadaPharmacyPro.com$0.920180$14.95$165.11
CanadaPharmacyPro.com$0.97090$14.95$87.41
GoldStarMeds.com$1.1030$0.00$33.09
InhalersOnline.com$1.12100$0.00$112.11
1800RxOnline.com$1.2330$0.00$36.77

Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.

Frequently asked questions

Is Mesalamine Er (Apriso) expensive if I don't have insurance?

Our most recent US pharmacy data shows a low of roughly $40.10 for Mesalamine Er with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.

Is Mesalamine Er (Apriso) available through Cost Plus Drugs?

Yes — Cost Plus Drugs lists Mesalamine Er at roughly $0.656 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.

What do Canadian pharmacies charge for Mesalamine Er (Apriso)?

We found Canadian pricing for Mesalamine Er starting near $0.040 per tablet in USD terms. That's before any shipping charge, which the table above breaks out separately.

Why is Mesalamine Er (Apriso) priced differently in the US and Canada?

Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the Canadian price coming in lower — but that isn't true for every drug, so it's worth checking each medication individually rather than assuming.

How much will I pay for Apriso with my insurance?

Your out-of-pocket cost for Apriso with insurance depends on your specific plan's formulary, deductible, and copay structure, so it can vary widely. It's advisable to check with your pharmacist or insurer for the exact amount. In some cases, the cash price for the generic version, potentially with a pharmacy savings program, could be lower than your insurance copay. You can ask your pharmacist to compare the pricing options available to you.

Are there generic alternatives to Apriso?

Yes. Apriso is the brand-name version of the drug mesalamine. Several pharmaceutical companies manufacture generic mesalamine extended-release capsules.

What is Apriso used for?

Apriso is prescribed to adults for the maintenance of remission in ulcerative colitis, a type of inflammatory bowel disease. It helps prevent the return of symptoms like rectal bleeding, abdominal pain, and diarrhea. As an aminosalicylate, its primary action is to reduce inflammation and swelling in the colon.