US pharmacy pricing
Where to Find the Cheapest Trikafta Price
Lowest price found · US pharmacies
$28,420.25/fill
for Trikafta, across the pharmacies in our data
US pharmacy prices — 84 tablets therapy pack
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $28,420.25Lowest | $28,423.25 | $284.42 |
 Harris Teeter Pharmacy | $28,420.25Lowest | $28,423.25 | $284.42 |
 Food Lion | $29,646.67 | $29,646.67 | $284.42 |
 Walgreens | $29,816.76 | $29,819.76 | $284.42 |
 Publix | $29,992.36 | $29,995.36 | $284.42 |
 Walmart Neighborhood Market | $30,512.90 | $30,515.90 | $284.42 |
 Walmart Pharmacy | $30,512.90 | $30,515.90 | $284.42 |
 Costco | $30,686.74 | $30,689.74 | $284.42 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Trikafta.
Frequently asked questions
How much does Trikafta (Trikafta) cost without insurance?
Our most recent US pharmacy data shows a low of roughly $28,420.25 for Trikafta with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.
Does Trikafta have a generic equivalent?
Generic and brand-name pricing for Trikafta is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
How much does Trikafta cost with insurance?
The cost of Trikafta with insurance varies significantly depending on your specific plan's formulary and coverage details. You should contact your insurance provider directly to confirm whether Trikafta is covered and to learn your exact copay or coinsurance amount. If your plan does not cover this medication, or if you have Medicare or Medicaid that does not provide coverage, you may be able to access lower prices at your local pharmacy through independent pharmacy savings programs. It can be helpful to compare the price available through such a program against your insurance copay to find the most affordable option.
Is generic Trikafta available?
Trikafta is a brand-name medication produced by Vertex Pharmaceuticals, Inc. As of now, there is no FDA-approved generic equivalent available on the market.